Three unbeaten top-25 teams play away from home this week, and one of them walks into a rematch. Georgia goes to Tuscaloosa ten months after holding Alabama to minus-3 rushing yards in the SEC title game. Indiana goes to a 5-0 Nebraska. UCLA goes to Autzen with Oregon still waiting on Dante Moore.
And Texas, the AP No. 1 with 61 first-place votes, meets Oklahoma in Dallas after both teams had a bye.
Below are our picks for all 58 FBS games this week, starting with the ten that matter most. They are our calls, not the room’s: voting is open on every game, twenty points a pick, and every vote counts toward your school on the fan leaderboard.
1. No. 2 Georgia at No. 6 Alabama
Saturday, 7:30 PM ET · ABC · Bryant-Denny Stadium
The last time these two met, Georgia won the SEC Championship Game 28-7 and held Alabama to minus-3 rushing yards. Both arrive 5-0. Gunner Stockton went 25 of 32 for 295 yards and three touchdowns in a 38-14 win over Vanderbilt, two of them to Dwight Phillips Jr. Alabama put 56 on Mississippi State on the road, held the Bulldogs to 18 rushing yards, and got two touchdown passes from Keelon Russell to Rico Scott.
The Tide’s run defense is the question it could not answer in December. It has answered it every week since.
Our pick: Alabama 27, Georgia 24.
Vote: Alabama vs. Georgia → · Compare the two programs
2. No. 1 Texas vs. Oklahoma
Saturday, 3:30 PM ET · ABC · Cotton Bowl, Dallas
Texas leads the Red River series 65-51-7 and won last year’s meeting 23-6. Arch Manning has 862 yards, seven touchdowns and three interceptions, and the Longhorns already own wins over Ohio State and Tennessee, with Colin Simmons collecting 5.5 sacks against the Vols. Oklahoma is 2-2, has lost the turnover battle 9-2 over its last three games, and may be without safety Michael Boganowski, left tackle Michael Fasusi and linebackers Owen Heinecke and Cole Sullivan. Brent Venables is 1-3 against Texas.
Our pick: Texas 27, Oklahoma 13.
3. No. 21 UCLA at No. 13 Oregon
Saturday, 3:30 PM ET · CBS · Autzen Stadium
Everything here hangs on Dante Moore, who left the USC game by ambulance after a targeting hit. Dan Lanning says Moore is “looking like he’s going to be OK.” If he cannot go, Dylan Raiola threw for 289 yards and two scores in relief. Moore started his college career at UCLA.
The Bruins are 4-0 for the first time since 2022 under Bob Chesney, coming off a 54-3 win over Maryland that was their largest Big Ten margin ever. Nico Iamaleava threw for 209 and Wayne Knight ran for 100.
Our pick: Oregon 31, UCLA 24.
Vote: Oregon vs. UCLA → · Compare the two programs
4. No. 7 Indiana at Nebraska
Saturday, 12:00 PM ET · FOX · Memorial Stadium
Two 5-0 teams, and only one of them is ranked. Indiana beat Rutgers 47-15 behind Josh Hoover’s four touchdown passes and a career-high 204 rushing yards from Turbo Richard. Nebraska beat Maryland 48-23 with Anthony Colandrea throwing for 238 and three scores and running for 108 more. Kwazi Gilmer caught 11 passes for 147 yards. Indiana goes to Ohio State next week, which makes this the trap the Hoosiers have to step around first.
Our pick: Indiana 34, Nebraska 24.
5. Texas A&M at No. 14 Missouri
Saturday, 12:00 PM ET · ABC · Faurot Field
Missouri beat then-No. 8 Florida 45-17, its first win over a top-10 team since 2013, and climbed eleven places in the poll. Austin Simmons threw for 340 and Jamal Roberts ran for 211 and three touchdowns. Texas A&M snapped its losing skid with a 34-7 win over Arkansas, a week after managing six points at LSU.
Our pick: Missouri 30, Texas A&M 20.
Vote: Missouri vs. Texas A&M →
6. No. 19 USC at Penn State
Saturday, 7:30 PM ET · NBC · Beaver Stadium (White Out)
USC came back from 21-10 down to beat Washington 25-21, sparked by Jahkeem Stewart’s 48-yard fumble return. Jayden Maiava threw for 245. Penn State is 0-2 in the Big Ten after a 34-13 loss at Northwestern, and the White Out is the place to find out whether that is a slide or a stumble.
Our pick: USC 27, Penn State 24.
7. No. 10 LSU at Kentucky
Saturday, 7:00 PM ET · ESPN · Kroger Field
Kentucky is 4-1 after coming back from 17 down to beat South Carolina 35-34 in overtime, when Will Stein went for two and Willie Rodriguez caught it. LSU has outscored its last two opponents 98-20, holding McNeese to 31 total yards and outgaining Texas A&M 506-197. The cheapest seat at Kroger Field is $229, second only to Tuscaloosa this week, which says what Lexington thinks of it.
Our pick: LSU 31, Kentucky 20.
8. No. 22 Houston at Kansas State
Saturday, 3:30 PM ET · FOX · Bill Snyder Family Stadium
Houston’s only loss is by two points at Texas Tech, and the Cougars run for 229.4 yards a game, 19th nationally. Kansas State is 3-1 under Collin Klein, coming off a bye after a 31-26 loss at Cincinnati, with Avery Johnson holding the school record of 55 career touchdown passes. The series is tied 1-1.
Our pick: Houston 27, Kansas State 24.
Vote on Houston at Kansas State →
9. No. 20 Iowa at Washington
Friday, 9:00 PM ET · Husky Stadium
Iowa’s first trip to Husky Stadium in 63 years comes with a quarterback question. Hank Brown left the 31-14 loss to Ohio State injured, and backup Jeremy Hecklinski went 5 for 5 in relief. Washington lost 25-21 at USC and is 0-2 in the conference.
Our pick: Washington 20, Iowa 17.
10. Florida State at Louisville
Friday, 7:00 PM ET · ESPN · L&N Federal Credit Union Stadium
Louisville is 2-3 with three losses by three points each: Ole Miss 41-38, Wake Forest 30-27 and NC State 31-28. It ranks 130th nationally against the pass. Florida State’s Ashton Daniels ran for 136 yards and five touchdowns in a 38-7 win over Virginia, and the defense had ten sacks.
Our pick: Florida State 31, Louisville 27.
Vote: Louisville vs. Florida State →
The rest of the FBS board
| Game | When (ET) | TV | Our pick |
| Southern Miss at Troy | Tue 8:00 | ESPN2 | Troy |
| Jacksonville State at Kennesaw State | Wed 7:00 | CBSSN | Jacksonville State |
| New Mexico State at FIU | Wed 7:30 | ESPN2 | FIU |
| Sam Houston at Liberty | Thu 7:00 | ESPNU | Liberty |
| Missouri State at Western Kentucky | Thu 7:00 | CBSSN | Western Kentucky |
| South Florida at UTSA | Thu 7:30 | ESPN | UTSA |
| South Alabama at Arkansas State | Thu 7:30 | ESPN2 | Arkansas State |
| Washington State at Utah State | Fri 9:00 | CW | Utah State |
| Wyoming at San José State | Fri 9:00 | CBSSN | San José State |
| Iowa State at No. 8 BYU | Fri 10:15 | ESPN | BYU |
| UCF at No. 18 Oklahoma State | Sat 12:00 | ESPN2 | Oklahoma State |
| North Carolina at No. 25 Pittsburgh | Sat 12:00 | ESPN | Pittsburgh |
| Arizona at West Virginia | Sat 12:00 | TNT | Arizona |
| Wake Forest at NC State | Sat 12:00 | CW | Wake Forest |
| Tulane at Army | Sat 12:00 | CBSSN | Army |
| Sacramento State at Bowling Green | Sat 12:00 | ESPN+ | Bowling Green |
| Ball State at Northwestern | Sat 12:30 | BTN | Northwestern |
| South Carolina at No. 16 Florida | Sat 12:45 | SECN | Florida |
| Old Dominion at App State | Sat 1:00 | ESPN+ | App State |
| Miami (OH) at UMass | Sat 2:00 | ESPN+ | Miami (OH) |
| Stanford at No. 3 Notre Dame | Sat 3:30 | NBC | Notre Dame |
| No. 9 Ole Miss at Vanderbilt | Sat 3:30 | ESPN | Ole Miss |
| Duke at Georgia Tech | Sat 3:30 | ESPN2 | Duke |
| Virginia Tech at California | Sat 3:30 | ACCN | Virginia Tech |
| Illinois at Michigan State | Sat 3:30 | FS1 | Illinois |
| Charlotte at North Texas | Sat 3:30 | ESPN+ | North Texas |
| Tulsa at Navy | Sat 3:30 | CBSSN | Navy |
| Eastern Michigan at Akron | Sat 3:30 | ESPN+ | Eastern Michigan |
| Buffalo at Toledo | Sat 3:30 | ESPN+ | Toledo |
| Central Michigan at Ohio | Sat 3:30 | ESPN+ | Ohio |
| Kent State at Western Michigan | Sat 3:30 | ESPN+ | Western Michigan |
| UConn at Temple | Sat 3:45 | ESPNU | Temple |
| Rice at East Carolina | Sat 4:00 | ESPN+ | East Carolina |
| Maryland at No. 5 Ohio State | Sat 4:15 | BTN | Ohio State |
| No. 15 Tennessee at Arkansas | Sat 4:15 | SECN | Tennessee |
| San Diego State at Oregon State | Sat 6:00 | USA | Oregon State |
| UAB at Memphis | Sat 7:00 | ESPN2 | Memphis |
| Nevada at UTEP | Sat 7:00 | FS1 | Nevada |
| North Dakota State at UNLV | Sat 7:00 | CW | North Dakota State |
| Coastal Carolina at Marshall | Sat 7:00 | ESPN+ | Marshall |
| Syracuse at Virginia | Sat 7:30 | ACCN | Virginia |
| Air Force at Northern Illinois | Sat 7:30 | CBSSN | Air Force |
| James Madison at Georgia Southern | Sat 7:30 | ESPNU | James Madison |
| Louisiana at Louisiana Tech | Sat 7:30 | ESPN+ | Louisiana Tech |
| Minnesota at Purdue | Sat 8:00 | BTN | Minnesota |
| Hawai’i at Arizona State | Sat 9:30 | FS1 | Arizona State |
| Kansas at No. 12 Utah | Sat 10:15 | ESPN | Utah |
| No. 23 Boise State at Fresno State | Sat 10:30 | CW | Boise State |
One to watch in that list: North Dakota State, winner of ten FCS titles, is 5-0 in its first season as an FBS member of the Mountain West and plays at UNLV in Las Vegas.
Cast your votes
Every game above is live on the Football Predictions board. Twenty points per vote, free to play, closing at kickoff.
The series continues with our FCS, Division II and Division III picks for Week 6. Commenting earns points too, which makes the Rally Pit the cheapest climb on the fan leaderboard.
